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Victoria Magrioti
Victoria Magrioti
Associate Professor of Chemistry, National and Kapodistrian University of Athens
Verifisert e-postadresse på chem.uoa.gr - Startside
Tittel
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Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
EA Dennis, J Cao, YH Hsu, V Magrioti, G Kokotos
Chemical reviews 111 (10), 6130-6185, 2011
12262011
Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages
L Gil-de-Gómez, AM Astudillo, C Guijas, V Magrioti, G Kokotos, ...
The Journal of Immunology 192 (2), 752-762, 2014
1562014
Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases
V Magrioti, G Kokotos
Expert opinion on therapeutic patents 20 (1), 1-18, 2010
1242010
Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis
A Kalyvas, C Baskakis, V Magrioti, V Constantinou-Kokotou, D Stephens, ...
Brain 132 (5), 1221-1235, 2009
1072009
Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-Independent Phospholipase A2
G Kokotos, YH Hsu, JE Burke, C Baskakis, CG Kokotos, V Magrioti, ...
Journal of medicinal chemistry 53 (9), 3602-3610, 2010
1022010
Structure−Activity Relationship of 2-Oxoamide Inhibition of Group IVA Cytosolic Phospholipase A2 and Group V Secreted Phospholipase A2
DA Six, E Barbayianni, V Loukas, V Constantinou-Kokotou, ...
Journal of medicinal chemistry 50 (17), 4222-4235, 2007
992007
Synthesis of Polyfluoro Ketones for Selective Inhibition of Human Phospholipase A2 Enzymes
C Baskakis, V Magrioti, N Cotton, D Stephens, V Constantinou-Kokotou, ...
Journal of medicinal chemistry 51 (24), 8027-8037, 2008
832008
Autotaxin inhibitors: a patent review
E Barbayianni, V Magrioti, P Moutevelis-Minakakis, G Kokotos
Expert opinion on therapeutic patents 23 (9), 1123-1132, 2013
772013
Phospholipase A2 inhibitors for the treatment of inflammatory diseases: a patent review (2010 – present)
V Magrioti, G Kokotos
Expert Opinion on Therapeutic Patents 23 (3), 333-344, 2013
672013
Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones in Vitro, ex Vivo, and in Vivo
G Kokotos, AJ Feuerherm, E Barbayianni, I Shah, M Sæther, V Magrioti, ...
Journal of medicinal chemistry 57 (18), 7523-7535, 2014
472014
Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice
RN Bone, Y Gai, V Magrioti, MG Kokotou, T Ali, X Lei, HM Tse, G Kokotos, ...
Diabetes 64 (2), 541-554, 2015
462015
Characterization of FKGK18 as Inhibitor of Group VIA Ca2+-Independent Phospholipase A2 (iPLA2β): Candidate Drug for Preventing Beta-Cell Apoptosis and …
T Ali, G Kokotos, V Magrioti, RN Bone, JA Mobley, W Hancock, ...
PloS one 8 (8), e71748, 2013
442013
New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2
V Magrioti, A Nikolaou, A Smyrniotou, I Shah, V Constantinou-Kokotou, ...
Bioorganic & medicinal chemistry 21 (18), 5823-5829, 2013
422013
Inhibition of secreted phospholipases A2 by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations
VD Mouchlis, V Magrioti, E Barbayianni, N Cermak, RC Oslund, ...
Bioorganic & medicinal chemistry 19 (2), 735-743, 2011
422011
Structure–activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes
G Antonopoulou, E Barbayianni, V Magrioti, N Cotton, D Stephens, ...
Bioorganic & medicinal chemistry 16 (24), 10257-10269, 2008
372008
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages
P Monge, A Garrido, JM Rubio, V Magrioti, G Kokotos, MA Balboa, ...
Biomolecules 10 (4), 542, 2020
332020
Synthetic inhibitors of group IVA and group VIA phospholipase A2
V Magrioti, G Kokotos
Anti Inflammatory and Anti Allergy Agents in Medicinal Chemistry 5 (2), 189, 2006
292006
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides
E Barbayianni, D Stephens, A Grkovich, V Magrioti, YH Hsu, P Dolatzas, ...
Bioorganic & medicinal chemistry 17 (13), 4833-4843, 2009
252009
2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2
MG Kokotou, G Galiatsatou, V Magrioti, G Koutoulogenis, E Barbayianni, ...
Scientific reports 7 (1), 7025, 2017
192017
Triacylglycerols Based on 2-(N-tert-Butoxycarbonylamino)oleic Acid Are Potent Inhibitors of Pancreatic Lipase
V Magrioti, R Verger, V Constantinou-Kokotou
Journal of medicinal chemistry 47 (2), 288-291, 2004
182004
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Artikler 1–20