Mathew Garnett

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Ultan McDermottChief Scientist, Oncology R&D, AstraZenecaVerifisert e-postadresse på astrazeneca.com
Francesco IorioHuman TechnopoleVerifisert e-postadresse på fht.org
Julio Saez RodriguezHeidelberg UniversityVerifisert e-postadresse på uni-heidelberg.de
Fiona M BehanDirector, GSKVerifisert e-postadresse på gsk.com
Emanuel GonçalvesINESC-ID & IST - Universidade de LisboaVerifisert e-postadresse på tecnico.ulisboa.pt
Kosuke YusaProfessor, Kyoto UniversityVerifisert e-postadresse på infront.kyoto-u.ac.jp
Rizwan AnsariUniversity of CambridgeVerifisert e-postadresse på cam.ac.uk
Lodewyk WesselsProfessor of Computational Cancer BiologyVerifisert e-postadresse på nki.nl
Euan StronachGSKVerifisert e-postadresse på gsk.com
Daniel A HaberProfessor of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical SchoolVerifisert e-postadresse på mgh.harvard.edu
Joshua E AllenOncoceuticsVerifisert e-postadresse på oncoceutics.com
Dieudonne J van der MeerSenior Scientist Bioinformatics - VitroScan BVVerifisert e-postadresse på vitroscan.nl
Patricia GreningerVerifisert e-postadresse på mgh.harvard.edu
David BarfordMRC Laboratory of Molecular BiologyVerifisert e-postadresse på mrc-lmb.cam.ac.uk
Michael P. MendenAssociate Professor, University of Melbourne, Department of Biochemistry and PharmacologyVerifisert e-postadresse på helmholtz-muenchen.de
Livio TrusolinoProfessor, University of Torino School of Medicine, ItalyVerifisert e-postadresse på ircc.it
Andrea BertottiUniversity of Torino - School of MedicineVerifisert e-postadresse på ircc.it
Graham Robert BignellSenior Staff Scientist, Wellcome Trust Sanger InstituteVerifisert e-postadresse på sanger.ac.uk
Matthew A. CoelhoWellcome Sanger InstituteVerifisert e-postadresse på sanger.ac.uk
Hans CleversHubrecht Institute - UtrechtVerifisert e-postadresse på hubrecht.eu

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Mathew Garnett

Wellcome Sanger Institute

Verifisert e-postadresse på sanger.ac.uk - Startside

cancer biology and therapeutics


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002	13028	2002
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF PTC Wan, MJ Garnett, SM Roe, S Lee, D Niculescu-Duvaz, VM Good, ... Cell 116 (6), 855-867, 2004	3379	2004
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells W Yang, J Soares, P Greninger, EJ Edelman, H Lightfoot, S Forbes, ... Nucleic acids research 41 (D1), D955-D961, 2012	3328	2012
Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012	2648	2012
Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015	2260	2015
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016	1896	2016
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ... Nature medicine 23 (12), 1424-1435, 2017	1311	2017
Guilty as charged: B-RAF is a human oncogene MJ Garnett, R Marais Cancer cell 6 (4), 313-319, 2004	1192	2004
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ... Nature 568 (7753), 511-516, 2019	1156	2019
Perturbation-response genes reveal signaling footprints in cancer gene expression M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ... Nature communications 9 (1), 20, 2018	643	2018
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ... PLoS one 8 (4), e61318, 2013	575	2013
Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization MJ Garnett, S Rana, H Paterson, D Barford, R Marais Molecular cell 20 (6), 963-969, 2005	519	2005
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ... Cell 151 (5), 937-950, 2012	498	2012
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ... Cell 167 (1), 260-274. e22, 2016	471	2016
High-content CRISPR screening C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ... Nature Reviews Methods Primers 2 (1), 1-23, 2022	452	2022
ETV6-NTRK3 Gene Fusions and Trisomy 11 Establish a Histogenetic Link between Mesoblastic Nephroma and Congenital Fibrosarcoma SR Knezevich, MJ Garnett, TJ Pysher, JB Beckwith, PE Grundy, ... Cancer research 58 (22), 5046-5048, 1998	439	1998
Characterizing mutational signatures in human cancer cell lines reveals episodic APOBEC mutagenesis M Petljak, LB Alexandrov, JS Brammeld, S Price, DC Wedge, ... Cell 176 (6), 1282-1294. e20, 2019	401	2019
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening E Driehuis, A Van Hoeck, K Moore, S Kolders, HE Francies, ... Proceedings of the National Academy of Sciences 116 (52), 26580-26590, 2019	395	2019
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019	315	2019
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics X Li, HE Francies, M Secrier, J Perner, A Miremadi, N Galeano-Dalmau, ... Nature communications 9 (1), 2983, 2018	314	2018

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