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Håvard Foyn
Håvard Foyn
Post Doc at the norwegian centre for molecular medicine
Verifisert e-postadresse på ncmm.uio.no
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NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility
A Drazic, H Aksnes, M Marie, M Boczkowska, S Varland, E Timmerman, ...
Proceedings of the National Academy of Sciences 115 (17), 4399-4404, 2018
1882018
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
G Liszczak, JM Goldberg, H Foyn, EJ Petersson, T Arnesen, ...
Nature structural & molecular biology 20 (9), 1098-1105, 2013
1572013
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of Nα-acetyltransferases and point to hNaa10p as the post-translational actin Nα …
P Van Damme, R Evjenth, H Foyn, K Demeyer, PJ De Bock, JR Lillehaug, ...
Molecular & Cellular Proteomics 10 (5), 2011
1552011
FOXK1 and FOXK2 regulate aerobic glycolysis
V Sukonina, H Ma, W Zhang, S Bartesaghi, S Subhash, M Heglind, ...
Nature 566 (7743), 279-283, 2019
1442019
Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80
M Goris, RS Magin, H Foyn, LM Myklebust, S Varland, R Ree, A Drazic, ...
Proceedings of the National Academy of Sciences 115 (17), 4405-4410, 2018
692018
Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors
H Foyn, JE Jones, D Lewallen, R Narawane, JE Varhaug, PR Thompson, ...
ACS chemical biology 8 (6), 1121-1127, 2013
572013
Crystal structure of the Golgi-associated human Nα-acetyltransferase 60 reveals the molecular determinants for substrate-specific acetylation
SI Støve, RS Magin, H Foyn, BE Haug, R Marmorstein, T Arnesen
Structure 24 (7), 1044-1056, 2016
522016
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
R Ree, LM Myklebust, P Thiel, H Foyn, KE Fladmark, T Arnesen
Bioscience reports 35 (5), e00249, 2015
522015
Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo
H Foyn, P Van Damme, SI Støve, N Glomnes, R Evjenth, K Gevaert, ...
Molecular & Cellular Proteomics 12 (1), 42-54, 2013
322013
DTNB-based quantification of in vitro enzymatic N-terminal acetyltransferase activity
H Foyn, PR Thompson, T Arnesen
Protein Terminal Profiling: Methods and Protocols, 9-15, 2017
282017
Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion
AL Ribeiro, RD Silva, H Foyn, MN Tiago, OS Rathore, T Arnesen, ...
Scientific reports 6 (1), 39118, 2016
212016
Characterization of Evolutionarily Conserved Trypanosoma cruzi NatC and NatA‐N‐Terminal Acetyltransferase Complexes
S Ochaya, O Franzén, DA Buhwa, H Foyn, CE Butler, SI Stove, KM Tyler, ...
Journal of parasitology research 2019 (1), 6594212, 2019
32019
Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
LM Myklebust, M Baumann, SI Støve, H Foyn, T Arnesen, BE Haug
Frontiers in Chemistry 11, 1202501, 2023
2023
Inhibitors
T Arnesen, BE Haug, LM Myklebust, F Havard
US Patent App. 16/956,776, 2020
2020
Inhibition of the actin N-terminal acetyltransferase NAA80
M Baumann, LM Myklebust, M Goris, R Magin, H Foyn, SI Stove, ...
FEBS OPEN BIO 8, 407-407, 2018
2018
Knockdown and inhibition of the N-terminal acetyltransferase Naa10/NatA in zebrafish
R Ree, LM Myklebust, H Foyn, SI Stove, BE Haug, T Arnesen
FEBS OPEN BIO 8, 422-422, 2018
2018
N-terminal acetylation of actin by NAA80 impacts cell migration
H Aksnes, A Drazic, M Marie, S Varland, E Timmerman, H Foyn, ...
FEBS OPEN BIO 8, 396-396, 2018
2018
Discovery of NAA80 as actin's N-terminal acetyltransferase-a novel regulator of cytoskeleton dynamics
A Drazic, H Aksnes, M Marie, M Boczkowska, S Varland, E Timmerman, ...
FEBS OPEN BIO 8, 409-409, 2018
2018
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Artikler 1–18