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Sharadha Dayalan Naidu
Sharadha Dayalan Naidu
Johns Hopkins University, University of Dundee
Verifisert e-postadresse på dundee.ac.uk
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107772021
Regulation of the mammalian heat shock factor 1
S Dayalan Naidu, AT Dinkova‐Kostova
The FEBS journal 284 (11), 1606-1627, 2017
1722017
Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection
SD Naidu, RV Kostov, AT Dinkova-Kostova
Trends in pharmacological sciences 36 (1), 6-14, 2015
1392015
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
L Quinti, S Dayalan Naidu, U Träger, X Chen, K Kegel-Gleason, D Llères, ...
Proceedings of the National Academy of Sciences 114 (23), E4676-E4685, 2017
1222017
KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy
T Shekh-Ahmad, R Eckel, S Dayalan Naidu, M Higgins, M Yamamoto, ...
Brain 141 (5), 1390-1403, 2018
1082018
KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease
S Dayalan Naidu, AT Dinkova-Kostova
Open biology 10 (6), 200105, 2020
842020
SIRT2-and NRF2-targeting thiazole-containing compound with therapeutic activity in Huntington's disease models
L Quinti, M Casale, S Moniot, TF Pais, MJ Van Kanegan, LS Kaltenbach, ...
Cell chemical biology 23 (7), 849-861, 2016
842016
Heat shock factor 1 is a substrate for p38 mitogen-activated protein kinases
S Dayalan Naidu, C Sutherland, Y Zhang, A Risco, L de la Vega, ...
Molecular and cellular biology 36 (18), 2403-2417, 2016
822016
Activation of Nrf2 signaling augments vesicular stomatitis virus oncolysis via autophagy-driven suppression of antiviral immunity
D Olagnier, RR Lababidi, SB Hadj, A Sze, Y Liu, SD Naidu, M Ferrari, ...
Molecular Therapy 25 (8), 1900-1916, 2017
792017
C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape
S Dayalan Naidu, A Muramatsu, R Saito, S Asami, T Honda, T Hosoya, ...
Scientific reports 8 (1), 8037, 2018
692018
Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response
DG Ryan, EV Knatko, AM Casey, JL Hukelmann, SD Naidu, AJ Brenes, ...
Iscience 25 (2), 2022
552022
Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1
S Dayalan Naidu, T Suzuki, M Yamamoto, JW Fahey, ...
Molecular nutrition & food research 62 (18), 1700908, 2018
512018
Transcription factors NRF2 and HSF1 have opposing functions in autophagy
S Dayalan Naidu, D Dikovskaya, E Gaurilcikaite, EV Knatko, ZR Healy, ...
Scientific reports 7 (1), 11023, 2017
362017
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation
Y Zhang, S Dayalan Naidu, K Samarasinghe, GC Van Hecke, A Pheely, ...
British journal of cancer 110 (1), 71-82, 2014
322014
Guidelines for the use and interpretation of assays for monitoring autophagy 1
D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1-382, 2021
312021
Downregulation of Keap1 confers features of a fasted metabolic state
EV Knatko, MH Tatham, Y Zhang, C Castro, M Higgins, SD Naidu, ...
IScience 23 (10), 2020
232020
Phenyl bis-sulfonamide Keap1-Nrf2 protein–protein interaction inhibitors with an alternative binding mode
N Georgakopoulos, S Talapatra, D Dikovskaya, S Dayalan Naidu, ...
Journal of Medicinal Chemistry 65 (10), 7380-7398, 2022
182022
The cell-permeable derivative of the immunoregulatory metabolite itaconate, 4-octyl itaconate, is anti-fibrotic in systemic sclerosis
J Henderson, S Dayalan Naidu, AT Dinkova-Kostova, S Przyborski, ...
Cells 10 (8), 2053, 2021
162021
Omaveloxolone (SkyclarysTM) for patients with Friedreich’s ataxia
SD Naidu, AT Dinkova-Kostova
Trends in Pharmacological Sciences, 2023
122023
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity
L Casares, R Moreno, KX Ali, M Higgins, SD Naidu, G Neill, L Cassin, ...
Redox Biology 51, 102291, 2022
122022
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Artikler 1–20