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Michael Zimmermann
Michael Zimmermann
Group Leader, EMBL
Verifisert e-postadresse på embl.de - Startside
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Mapping human microbiome drug metabolism by gut bacteria and their genes
M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman
Nature 570 (7762), 462-467, 2019
8042019
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine
BB Williams, AH Van Benschoten, P Cimermancic, MS Donia, ...
Cell host & microbe 16 (4), 495-503, 2014
5452014
Separating host and microbiome contributions to drug pharmacokinetics and toxicity
M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman
Science 363 (6427), eaat9931, 2019
3242019
Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis
S Watanabe, M Zimmermann, MB Goodwin, U Sauer, CE Barry 3rd, ...
PLoS pathogens 7 (10), e1002287, 2011
2582011
Absolute proteome composition and dynamics during dormancy and resuscitation of Mycobacterium tuberculosis
OT Schubert, C Ludwig, M Kogadeeva, M Zimmermann, G Rosenberger, ...
Cell host & microbe 18 (1), 96-108, 2015
2202015
Unravelling the collateral damage of antibiotics on gut bacteria
L Maier, CV Goemans, J Wirbel, M Kuhn, C Eberl, M Pruteanu, P Müller, ...
Nature 599 (7883), 120-124, 2021
1922021
Bioaccumulation of therapeutic drugs by human gut bacteria
M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ...
Nature 597 (7877), 533-538, 2021
1872021
Engineered regulatory systems modulate gene expression of human commensals in the gut
B Lim, M Zimmermann, NA Barry, AL Goodman
Cell 169 (3), 547-558. e15, 2017
1752017
Nontargeted metabolomics reveals the multilevel response to antibiotic perturbations
M Zampieri, M Zimmermann, M Claassen, U Sauer
Cell reports 19 (6), 1214-1228, 2017
1552017
High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection
J De Smet, M Zimmermann, M Kogadeeva, PJ Ceyssens, W Vermaelen, ...
The ISME journal 10 (8), 1823-1835, 2016
1422016
Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response
Y Uchimura, T Fuhrer, H Li, MA Lawson, M Zimmermann, B Yilmaz, ...
Immunity 49 (3), 545-559. e5, 2018
1342018
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
A Chevallereau, BG Blasdel, J De Smet, M Monot, M Zimmermann, ...
PLoS genetics 12 (7), e1006134, 2016
1122016
Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice
SY Wotzka, M Kreuzer, L Maier, M Arnoldini, BD Nguyen, AO Brachmann, ...
Nature Microbiology 4 (12), 2164-2174, 2019
1082019
A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus
M Zimmermann, MA Fischbach
Chemistry & biology 17 (9), 925-930, 2010
1032010
Integration of metabolomics and transcriptomics reveals a complex diet of Mycobacterium tuberculosis during early macrophage infection
M Zimmermann, M Kogadeeva, M Gengenbacher, G McEwen, ...
MSystems 2 (4), 10.1128/msystems. 00057-17, 2017
972017
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
B Rieck, G Degiacomi, M Zimmermann, A Cascioferro, F Boldrin, ...
PLoS pathogens 13 (5), e1006399, 2017
892017
Towards a mechanistic understanding of reciprocal drug–microbiome interactions
M Zimmermann, KR Patil, A Typas, L Maier
Molecular systems biology 17 (3), e10116, 2021
712021
Quantification and mass isotopomer profiling of α-keto acids in central carbon metabolism
M Zimmermann, U Sauer, N Zamboni
Analytical chemistry 86 (6), 3232-3237, 2014
702014
Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation
M Schmaler, A Colone, J Spagnuolo, M Zimmermann, M Lepore, ...
Mucosal immunology 11 (4), 1060-1070, 2018
662018
The stringent response determines the ability of a commensal bacterium to survive starvation and to persist in the gut
WB Schofield, M Zimmermann-Kogadeeva, M Zimmermann, NA Barry, ...
Cell host & microbe 24 (1), 120-132. e6, 2018
612018
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Artikler 1–20