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Karim Zuhra
Karim Zuhra
Postdoctoral Researcher, Faculty of Medicine & Science, University of Fribourg, Switzerland
Verified email at unifr.ch
Title
Cited by
Cited by
Year
Cystathionine-β-synthase: molecular regulation and pharmacological inhibition
K Zuhra, F Augsburger, T Majtan, C Szabo
Biomolecules 10 (5), 697, 2020
1452020
Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells
K Ascenção, N Dilek, F Augsburger, T Panagaki, K Zuhra, C Szabo
Pharmacological Research 165, 105393, 2021
442021
Physiological concentrations of cyanide stimulate mitochondrial Complex IV and enhance cellular bioenergetics
EB Randi, K Zuhra, L Pecze, T Panagaki, C Szabo
Proceedings of the National Academy of Sciences 118 (20), e2026245118, 2021
372021
N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells
K Zuhra, CS Tomé, L Masi, G Giardina, G Paulini, F Malagrinò, E Forte, ...
Cells 8 (8), 828, 2019
372019
Hydrogen sulfide oxidation: adaptive changes in mitochondria of SW480 colorectal cancer cells upon exposure to hypoxia
F Malagrinò, K Zuhra, L Mascolo, D Mastronicola, JB Vicente, E Forte, ...
Oxidative Medicine and Cellular Longevity 2019, 2019
352019
The two faces of cyanide: an environmental toxin and a potential novel mammalian gasotransmitter
K Zuhra, C Szabo
The FEBS journal 289 (9), 2481-2515, 2022
342022
Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down …
T Panagaki, L Lozano-Montes, L Janickova, K Zuhra, MP Szabo, T Majtan, ...
Redox Biology 51, 102233, 2022
322022
Hydrogen sulfide metabolism and signaling in the tumor microenvironment
A Giuffrè, CS Tomé, DGF Fernandes, K Zuhra, JB Vicente
Tumor Microenvironment: The Main Driver of Metabolic Adaptation, 335-353, 2020
322020
The multifaceted roles of sulfane sulfur species in cancer-associated processes
K Zuhra, CS Tomé, E Forte, JB Vicente, A Giuffrè
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1862 (2), 148338, 2021
262021
Mechanism of cystathionine-β-synthase inhibition by disulfiram: The role of bis (N, N-diethyldithiocarbamate)-copper (II)
K Zuhra, T Panagaki, EB Randi, F Augsburger, M Blondel, G Friocourt, ...
Biochemical pharmacology 182, 114267, 2020
262020
The role of organosulfur compounds as Nrf2 activators and their antioxidant effects
MC Egbujor, M Petrosino, K Zuhra, L Saso
Antioxidants 11 (7), 1255, 2022
222022
H2S biogenesis by cystathionine beta-synthase: mechanism of inhibition by aminooxyacetic acid and unexpected role of serine
M Petrosino, K Zuhra, J Kopec, A Hutchin, C Szabo, T Majtan
Cellular and Molecular Life Sciences 79 (8), 438, 2022
162022
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity
A Katsouda, D Valakos, VS Dionellis, SI Bibli, I Akoumianakis, S Karaliota, ...
Journal of Experimental Medicine 219 (7), e20211894, 2022
162022
Screening pyridine derivatives against human hydrogen sulfide-synthesizing enzymes by orthogonal methods
K Zuhra, PMF Sousa, G Paulini, AR Lemos, Z Kalme, I Bisenieks, ...
Scientific Reports 9 (1), 684, 2019
132019
Sequential accumulation of ‘driver’pathway mutations induces the upregulation of hydrogen-sulfide-producing enzymes in human colonic epithelial cell organoids
K Ascenção, N Dilek, K Zuhra, K Módis, T Sato, C Szabo
Antioxidants 11 (9), 1823, 2022
112022
Cytoglobin silencing promotes melanoma malignancy but sensitizes for ferroptosis and pyroptosis therapy response
J De Backer, D Maric, K Zuhra, A Bogaerts, C Szabo, W Vanden Berghe, ...
Antioxidants 11 (8), 1548, 2022
102022
Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action
K Zuhra, M Petrosino, B Gupta, T Panagaki, M Cecconi, ...
Nitric Oxide 128, 12-24, 2022
72022
Inhibition of the 3-mercaptopyruvate sulfurtransferase—Hydrogen sulfide system promotes cellular lipid accumulation
G Casili, E Randi, T Panagaki, K Zuhra, M Petrosino, C Szabo
Geroscience 44 (4), 2271-2289, 2022
72022
Human Cystathionine γ-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H2S
DGF Fernandes, J Nunes, CS Tomé, K Zuhra, JMF Costa, AMM Antunes, ...
Antioxidants 10 (9), 1391, 2021
72021
Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells
SS Santos, LOCP Rodrigues, V Martins, M Petrosino, K Zuhra, ...
Antioxidants 12 (3), 647, 2023
52023
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Articles 1–20