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Glen Ropella
Glen Ropella
Tempus Dictum, Inc.
Verified email at tempusdictum.com - Homepage
Title
Cited by
Cited by
Year
Open-ended evolution: Perspectives from the OEE workshop in York
T Taylor, M Bedau, A Channon, D Ackley, W Banzhaf, G Beslon, E Dolson, ...
Artificial life 22 (3), 408-423, 2016
1412016
At the biological modeling and simulation frontier
CA Hunt, GEP Ropella, TN Lam, J Tang, SHJ Kim, JA Engelberg, ...
Pharmaceutical research 26, 2369-2400, 2009
1012009
Physiologically based synthetic models of hepatic disposition
CA Hunt, GEP Ropella, L Yan, DY Hung, MS Roberts
Journal of pharmacokinetics and pharmacodynamics 33, 737-772, 2006
772006
Essential operating principles for tumor spheroid growth
JA Engelberg, GEP Ropella, CA Hunt
BMC systems biology 2, 1-19, 2008
622008
Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver
L Yan, GEP Ropella, S Park, MS Roberts, CA Hunt
Pharmaceutical research 25, 1023-1036, 2008
612008
Dichotomies between computational and mathematical models
CA Hunt, GEP Ropella, S Park, J Engelberg
Nature biotechnology 26 (7), 737-738, 2008
522008
Software engineering considerations for individual‐based models
GE Ropella, SF Railsback, SK Jackson
Natural Resource Modeling 15 (1), 5-22, 2002
502002
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity
CA Hunt, RC Kennedy, SHJ Kim, GEP Ropella
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5 (4), 461-480, 2013
492013
Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model
L Yan, S Sheihk-Bahaei, S Park, GEP Ropella, CA Hunt
Drug metabolism and disposition 36 (4), 759-768, 2008
442008
Tracing multiscale mechanisms of drug disposition in normal and diseased livers
S Park, SHJ Kim, GEP Ropella, MS Roberts, CA Hunt
Journal of Pharmacology and Experimental Therapeutics 334 (1), 124-136, 2010
352010
Relational grounding facilitates development of scientifically useful multiscale models
CA Hunt, GEP Ropella, T Lam, AD Gewitz
Theoretical Biology and Medical Modelling 8, 1-23, 2011
332011
Toward modular biological models: defining analog modules based on referent physiological mechanisms
BK Petersen, GEP Ropella, CA Hunt
BMC systems biology 8, 1-18, 2014
322014
Competing mechanistic hypotheses of acetaminophen-induced hepatotoxicity challenged by virtual experiments
AK Smith, BK Petersen, GEP Ropella, RC Kennedy, N Kaplowitz, ...
PloS computational biology 12 (12), e1005253, 2016
282016
Computational strategies unravel and trace how liver disease changes hepatic drug disposition
S Park, GEP Ropella, SHJ Kim, MS Roberts, CA Hunt
Journal of Pharmacology and Experimental Therapeutics 328 (1), 294-305, 2009
282009
Using heuristic models to bridge the gap between analytic and experimental models in biology
GE Ropella, CA Hunt, DA Nag
Agent-Directed Simulation Symposium, Vol. Simulation Series 37 (2), 182-190, 2005
262005
Similarity measures for automated comparison of in silico and in vitro experimental results
GEP Ropella, DA Nag, CA Hunt
Proceedings of the 25th Annual International Conference of the IEEE …, 2003
222003
Cloud computing and validation of expandable in silico livers
GEP Ropella, CA Hunt
BMC systems biology 4, 1-13, 2010
192010
Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms
AK Smith, GEP Ropella, MR McGill, P Krishnan, L Dutta, RC Kennedy, ...
PLoS computational biology 16 (6), e1007622, 2020
182020
Methodological considerations of heuristic modeling of biological systems
GEP Ropella, CA Hunt, S Sheikh-Bahaei
Proceedings of the 9th world multi-conference on systemics, cybernetics and …, 2005
182005
Biomimetic in silico devices
CA Hunt, GEP Ropella, MS Roberts, L Yan
Computational Methods in Systems Biology: International Conference CMSB 2004 …, 2005
162005
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