Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 T Herold, V Jurinovic, C Arnreich, BJ Lipworth, JC Hellmuth, ... Journal of Allergy and Clinical Immunology 146 (1), 128-136. e4, 2020 | 1076 | 2020 |
5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I A Schmidt, T Schwerd, W Hamm, JC Hellmuth, S Cui, M Wenzel, ... Proceedings of the National Academy of Sciences 106 (29), 12067-12072, 2009 | 541 | 2009 |
Immunothrombotic dysregulation in COVID-19 pneumonia is associated with respiratory failure and coagulopathy L Nicolai, A Leunig, S Brambs, R Kaiser, T Weinberger, M Weigand, ... Circulation 142 (12), 1176-1189, 2020 | 534 | 2020 |
5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma H Poeck, R Besch, C Maihoefer, M Renn, D Tormo, SS Morskaya, ... Nature medicine 14 (11), 1256-1263, 2008 | 483 | 2008 |
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA DA Pippig, JC Hellmuth, S Cui, A Kirchhofer, K Lammens, A Lammens, ... Nucleic acids research 37 (6), 2014-2025, 2009 | 210 | 2009 |
Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein A Greinacher, K Selleng, J Mayerle, R Palankar, J Wesche, S Reiche, ... Blood, The Journal of the American Society of Hematology 138 (14), 1269-1277, 2021 | 118 | 2021 |
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin … DA Eichenauer, A Plütschow, S Kreissl, M Sökler, JC Hellmuth, ... The Lancet Oncology 18 (12), 1680-1687, 2017 | 118 | 2017 |
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia L Nicolai, A Leunig, S Brambs, R Kaiser, M Joppich, ML Hoffknecht, ... Journal of Thrombosis and Haemostasis 19 (2), 574-581, 2021 | 90 | 2021 |
Myocardial inflammation and dysfunction in COVID-19–associated myocardial injury LT Weckbach, A Curta, S Bieber, A Kraechan, J Brado, JC Hellmuth, ... Circulation: Cardiovascular Imaging 14 (1), e012220, 2021 | 85 | 2021 |
Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19 R Kaiser, A Leunig, K Pekayvaz, O Popp, M Joppich, V Polewka, R Escaig, ... JCI insight 6 (18), 2021 | 82 | 2021 |
Liver function test abnormalities at hospital admission are associated with severe course of SARS-CoV-2 infection: a prospective cohort study S Weber, JC Hellmuth, C Scherer, M Muenchhoff, J Mayerle, AL Gerbes Gut 70 (10), 1925-1932, 2021 | 81 | 2021 |
Impaired function and delayed regeneration of dendritic cells in COVID-19 E Winheim, L Rinke, K Lutz, A Reischer, A Leutbecher, L Wolfram, ... PLoS pathogens 17 (10), e1009742, 2021 | 71 | 2021 |
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles JC Hellmuth, A Louissaint Jr, M Szczepanowski, S Haebe, A Pastore, ... Blood, The Journal of the American Society of Hematology 132 (16), 1695-1702, 2018 | 60 | 2018 |
Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury S Bieber, A Kraechan, JC Hellmuth, M Muenchhoff, C Scherer, ... Infection 49, 491-500, 2021 | 54 | 2021 |
COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma E Gaitzsch, V Passerini, E Khatamzas, CD Strobl, M Muenchhoff, ... HemaSphere 5 (7), 2021 | 47 | 2021 |
Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients D Munker, A Osterman, H Stubbe, M Muenchhoff, T Veit, T Weinberger, ... European Respiratory Journal 58 (1), 2021 | 44 | 2021 |
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML C Duy, M Teater, FE Garrett-Bakelman, TC Lee, C Meydan, JL Glass, M Li, ... Cancer discovery 9 (7), 872-889, 2019 | 43 | 2019 |
Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses PR Wratil, NA Schmacke, B Karakoc, A Dulovic, D Junker, M Becker, ... Cell reports 37 (13), 2021 | 39 | 2021 |
Pulmonary function impairment of asymptomatic and persistently symptomatic patients 4 months after COVID-19 according to disease severity D Munker, T Veit, J Barton, P Mertsch, C Mümmler, A Osterman, ... Infection, 1-12, 2021 | 39 | 2021 |
Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus FS Hoffmann, A Schmidt, MD Chevillotte, C Wisskirchen, J Hellmuth, ... Hepatology 61 (2), 460-470, 2015 | 39 | 2015 |