| RNAi factors are present and active in human cell nuclei KT Gagnon, L Li, Y Chu, BA Janowski, DR Corey Cell reports 6 (1), 211-221, 2014 | 398 | 2014 |
| Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs J Hu, M Matsui, KT Gagnon, JC Schwartz, S Gabillet, K Arar, J Wu, ... Nature biotechnology 27 (5), 478-484, 2009 | 263 | 2009 |
| Promoter RNA links transcriptional regulation of inflammatory pathway genes M Matsui, Y Chu, H Zhang, KT Gagnon, S Shaikh, S Kuchimanchi, ... Nucleic acids research 41 (22), 10086-10109, 2013 | 211 | 2013 |
| Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading KT Gagnon, L Li, BA Janowski, DR Corey Nature protocols 9 (9), 2045-2060, 2014 | 196 | 2014 |
| Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat KT Gagnon, HM Pendergraff, GF Deleavey, EE Swayze, P Potier, ... Biochemistry 49 (47), 10166-10178, 2010 | 161 | 2010 |
| Transcriptional regulation by small RNAs at sequences downstream from 3′ gene termini X Yue, JC Schwartz, Y Chu, ST Younger, KT Gagnon, S Elbashir, ... Nature chemical biology 6 (8), 621-629, 2010 | 121 | 2010 |
| Argonaute and the nuclear RNAs: new pathways for RNA-mediated control of gene expression KT Gagnon, DR Corey Nucleic acid therapeutics 22 (1), 3-16, 2012 | 86 | 2012 |
| Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity D O’Reilly, ZJ Kartje, EA Ageely, E Malek-Adamian, M Habibian, ... Nucleic acids research 47 (2), 546-558, 2018 | 77 | 2018 |
| Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity KT Gagnon Nucleic Acids Research, 2018 | 77 | 2018 |
| RNA biology of disease-associated microsatellite repeat expansions KJ Rohilla, KT Gagnon Acta Neuropathologica Communications 5 (1), 63, 2017 | 77 | 2017 |
| A dimeric structure for archaeal box C/D small ribonucleoproteins F Bleichert, KT Gagnon, BA Brown, ES Maxwell, AE Leschziner, ... Science 325 (5946), 1384-1387, 2009 | 71 | 2009 |
| II, Maxwell ES, Leschziner AE, Unger VM, Baserga SJ. 2009. A dimeric structure for archaeal box C/D small ribonucleoproteins F Bleichert, KT Gagnon, BA Brown Science 325, 1384-1387, 0 | 71* | |
| Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs J Hu, KT Gagnon, J Liu, JK Watts, J Syeda-Nawaz, CF Bennett, ... Biological chemistry 392 (4), 315-325, 2011 | 69 | 2011 |
| Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells R Kalantari, JA Hicks, L Li, KT Gagnon, V Sridhara, A Lemoff, H Mirzaei, ... RNA 22 (7), 1085-1098, 2016 | 65 | 2016 |
| Digital quantitation of potential therapeutic target RNAs DW Dodd, KT Gagnon, DR Corey Nucleic acid therapeutics 23 (3), 188-194, 2013 | 64 | 2013 |
| Antisense and antigene inhibition of gene expression by cell-permeable oligonucleotide–oligospermine conjugates KT Gagnon, JK Watts, HM Pendergraff, C Montaillier, D Thai, P Potier, ... Journal of the American Chemical Society 133 (22), 8404-8407, 2011 | 54 | 2011 |
| Chimeric Guides Probe and Enhance Cas9 Biochemical Activity ZJ Kartje, CL Barkau, KJ Rohilla, EA Ageely, KT Gagnon Biochemistry, 2018 | 47 | 2018 |
| Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs KT Gagnon, DR Corey nucleic acid therapeutics 29 (3), 116-122, 2019 | 45 | 2019 |
| Signature amino acids enable the archaeal L7Ae box C/D RNP core protein to recognize and bind the K-loop RNA motif KT Gagnon, X Zhang, G Qu, S Biswas, J Suryadi, BA Brown, ES Maxwell Rna 16 (1), 79-90, 2010 | 42 | 2010 |
| Pathogenic C9ORF72 antisense repeat RNA forms a double helix with tandem C: C mismatches DW Dodd, DR Tomchick, DR Corey, KT Gagnon Biochemistry 55 (9), 1283-1286, 2016 | 37 | 2016 |
