Jeremy K Nicholson

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Elaine HolmesMurdoch University & Imperial College LondonVerified email at imperial.ac.uk
Lindon JCVerified email at imperial.ac.uk
Ian D WilsonImperial College, LondonVerified email at imperial.ac.uk
James KinrossImperial College LondonVerified email at imperial.ac.uk
Marc-Emmanuel Dumas, PhD, FRSB,...Professor, Chair in Systems Medicine, Imperial College London, Director of Research, CNRSVerified email at imperial.ac.uk
Olivier CloarecPrincipal Research Scientist, Sartorius Corporate ResearchVerified email at sartorius.com
Hector KeunProfessor of Biochemistry, Imperial College LondonVerified email at imperial.ac.uk
Paul ElliottProfessor of Epidemiology and Public Health, Imperial College LondonVerified email at imperial.ac.uk
Ara DarziProfessor of SurgeryVerified email at imperial.ac.uk
Jia LiImperial College LondonVerified email at imperial.ac.uk
Queenie ChanSchool of Public Health, Imperial College LondonVerified email at imperial.ac.uk
Ruey Leng LooMurdoch UniversityVerified email at murdoch.edu.au
Prof. J.L. GriffinDirector of the Rowett InstituteVerified email at abdn.ac.uk
Huiru TangWuhan Institute of Physics and MathematicsVerified email at wipm.ac.cn
Yap, Ivan KSImperial College London; Sarawak Research and Development Council; Clinical Research Centre SarawakVerified email at clinicalresearch.my
Henrik AnttiDepartment of Chemsitry, Umeå University, SwedenVerified email at chem.umu.se
J. M. PosmaSenior Lecturer in Biomedical Informatics, Imperial College LondonVerified email at imperial.ac.uk
Francois-Pierre MARTINH&H GroupVerified email at hh.global
Serge RezziSwiss Nutrition and Health foundationVerified email at nutritionhealthfoundation.ch
Luke WhileyMurdoch UniversityVerified email at murdoch.edu.au

Jeremy K Nicholson

Australian National Phenome Center, Murdoch University + Imperial College London

Verified email at murdoch.edu.au - Homepage

mass spectrometry analytical chemistry NMR metabonomics metabolomics


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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data JK Nicholson, JC Lindon, E Holmes Xenobiotica 29 (11), 1181-1189, 1999	5103	1999
Host-gut microbiota metabolic interactions JK Nicholson, E Holmes, J Kinross, R Burcelin, G Gibson, W Jia, ... Science 336 (6086), 1262-1267, 2012	4932	2012
Metabonomics: a platform for studying drug toxicity and gene function JK Nicholson, J Connelly, JC Lindon, E Holmes Nature reviews Drug discovery 1 (2), 153-161, 2002	2596	2002
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692, 2007	2347	2007
Metabonomics JK Nicholson, JC Lindon Nature 455 (7216), 1054-1056, 2008	2290	2008
OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006	1544	2006
Impact of the gut microbiota on inflammation, obesity, and metabolic disease CL Boulangé, AL Neves, J Chilloux, JK Nicholson, ME Dumas Genome medicine 8, 1-12, 2016	1443	2016
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics JT Brindle, H Antti, E Holmes, G Tranter, JK Nicholson, HWL Bethell, ... Nature medicine 8 (12), 1439-1445, 2002	1440	2002
Understanding'global'systems biology: metabonomics and the continuum of metabolism JK Nicholson, ID Wilson Nature Reviews Drug Discovery 2 (8), 668-676, 2003	1428	2003
Symbiotic gut microbes modulate human metabolic phenotypes M Li, B Wang, M Zhang, M Rantalainen, S Wang, H Zhou, Y Zhang, ... Proceedings of the National Academy of Sciences 105 (6), 2117-2122, 2008	1363	2008
Gut microbiomes of Malawian twin pairs discordant for kwashiorkor MI Smith, T Yatsunenko, MJ Manary, I Trehan, R Mkakosya, J Cheng, ... Science 339 (6119), 548-554, 2013	1303	2013
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ... Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006	1292	2006
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma JK Nicholson, PJD Foxall, M Spraul, RD Farrant, JC Lindon Analytical chemistry 67 (5), 793-811, 1995	1222	1995
Human metabolic phenotype diversity and its association with diet and blood pressure E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ... Nature 453 (7193), 396-400, 2008	1216	2008
Gut microorganisms, mammalian metabolism and personalized health care JK Nicholson, E Holmes, ID Wilson Nature Reviews Microbiology 3 (5), 431-438, 2005	1202	2005
Global metabolic profiling procedures for urine using UPLC–MS EJ Want, ID Wilson, H Gika, G Theodoridis, RS Plumb, J Shockcor, ... Nature protocols 5 (6), 1005-1018, 2010	1126	2010
Pharmaco-metabonomic phenotyping and personalized drug treatment T Andrew Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ... Nature 440 (7087), 1073-1077, 2006	1064	2006
Fat, fibre and cancer risk in African Americans and rural Africans SJD O’Keefe, JV Li, L Lahti, J Ou, F Carbonero, K Mohammed, JM Posma, ... Nature communications 6 (1), 1-14, 2015	1034	2015
Global metabolic profiling of animal and human tissues via UPLC-MS EJ Want, P Masson, F Michopoulos, ID Wilson, G Theodoridis, RS Plumb, ... Nature protocols 8 (1), 17-32, 2013	1033	2013
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ... Analytical chemistry 77 (5), 1282-1289, 2005	1032	2005

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