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Douglas Huseby
Douglas Huseby
Researcher, Uppsala University
Verifisert e-postadresse på imbim.uu.se - Startside
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Gut inflammation provides a respiratory electron acceptor for Salmonella
SE Winter, P Thiennimitr, MG Winter, BP Butler, DL Huseby, RW Crawford, ...
Nature 467 (7314), 426-429, 2010
14332010
Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota
P Thiennimitr, SE Winter, MG Winter, MN Xavier, V Tolstikov, DL Huseby, ...
Proceedings of the National Academy of Sciences 108 (42), 17480-17485, 2011
7082011
Odilorhabdins, antibacterial agents that cause miscoding by binding at a new ribosomal site
L Pantel, T Florin, M Dobosz-Bartoszek, E Racine, M Sarciaux, M Serri, ...
Molecular cell 70 (1), 83-94. e7, 2018
1492018
Mutation Supply and Relative Fitness Shape the Genotypes of Ciprofloxacin-Resistant Escherichia coli
DL Huseby, F Pietsch, G Brandis, L Garoff, A Tegehall, D Hughes
Molecular biology and evolution 34 (5), 1029-1039, 2017
1182017
In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii
M Juhas, E Widlake, J Teo, DL Huseby, JM Tyrrell, YS Polikanov, O Ercan, ...
Journal of Antimicrobial Chemotherapy 74 (4), 944-952, 2019
1072019
Retrovirus capsid protein assembly arrangements
K Mayo, D Huseby, J McDermott, B Arvidson, L Finlay, E Barklis
Journal of molecular biology 325 (1), 225-237, 2003
882003
Evidence that a metabolic microcompartment contains and recycles private cofactor pools
DL Huseby, JR Roth
Journal of bacteriology 195 (12), 2864-2879, 2013
852013
Ciprofloxacin selects for RNA polymerase mutations with pleiotropic antibiotic resistance effects
F Pietsch, JM Bergman, G Brandis, LL Marcusson, A Zorzet, DL Huseby, ...
Journal of Antimicrobial Chemotherapy 72 (1), 75-84, 2016
782016
Assembly of human immunodeficiency virus precursor gag proteins
D Huseby, RL Barklis, A Alfadhli, E Barklis
Journal of Biological Chemistry 280 (18), 17664-17670, 2005
762005
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
A Alfadhli, D Huseby, E Kapit, D Colman, E Barklis
Journal of virology 81 (3), 1472-1478, 2007
732007
Evaluating the potential efficacy and limitations of a phage for joint antibiotic and phage therapy of Staphylococcus aureus infections
BA Berryhill, DL Huseby, IC McCall, D Hughes, BR Levin
Proceedings of the National Academy of Sciences 118 (10), 2021
672021
Virus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domain
I Scholz, B Arvidson, D Huseby, E Barklis
Journal of virology 79 (3), 1470-1479, 2005
622005
Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
L Praski Alzrigat, DL Huseby, G Brandis, D Hughes
Journal of Antimicrobial Chemotherapy 72 (11), 3016-3024, 2017
562017
Alternative Evolutionary Pathways for Drug-Resistant Small Colony Variant Mutants in Staphylococcus aureus
S Cao, DL Huseby, G Brandis, D Hughes
MBio 8 (3), 10.1128/mbio. 00358-17, 2017
55*2017
Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli
L Garoff, F Pietsch, DL Huseby, T Lilja, G Brandis, D Hughes
Molecular biology and evolution 37 (6), 1637-1646, 2020
502020
Analysis of Rous sarcoma virus capsid protein variants assembled on lipid monolayers
K Mayo, ML Vana, J McDermott, D Huseby, J Leis, E Barklis
Journal of molecular biology 316 (3), 667-678, 2002
452002
Effect of aminoacyl-tRNA synthetase mutations on susceptibility to ciprofloxacin in Escherichia coli
L Garoff, DL Huseby, L Praski Alzrigat, D Hughes
Journal of Antimicrobial Chemotherapy 73 (12), 3285-3292, 2018
332018
Discovery and hit-to-lead optimization of benzothiazole scaffold-based DNA gyrase inhibitors with potent activity against Acinetobacter baumannii and Pseudomonas aeruginosa
AE Cotman, M Durcik, D Benedetto Tiz, F Fulgheri, D Secci, M Sterle, ...
Journal of medicinal chemistry 66 (2), 1380-1425, 2023
292023
Antibiotic resistance by high-level intrinsic suppression of a frameshift mutation in an essential gene
DL Huseby, G Brandis, L Praski Alzrigat, D Hughes
Proceedings of the National Academy of Sciences 117 (6), 3185-3191, 2020
292020
New dual inhibitors of bacterial topoisomerases with broad-spectrum antibacterial activity and in vivo efficacy against vancomycin-intermediate Staphylococcus aureus
M Durcik, AE Cotman, Z Toplak, S Mozina, Z Skok, PE Szili, M Czikkely, ...
Journal of medicinal chemistry 66 (6), 3968-3994, 2023
222023
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