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W. K. Alfred Yung
W. K. Alfred Yung
Verifisert e-postadresse på mdanderson.org
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
73192008
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
cell 155 (2), 462-477, 2013
49162013
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
PA Steck, MA Pershouse, SA Jasser, WKA Yung, H Lin, AH Ligon, ...
Nature genetics 15 (4), 356-362, 1997
41241997
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
Journal of clinical oncology 27 (28), 4733-4740, 2009
29222009
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ...
Cell 164 (3), 550-563, 2016
19802016
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
ET Wong, KR Hess, MJ Gleason, KA Jaeckle, AP Kyritsis, MD Prados, ...
Journal of Clinical Oncology 17 (8), 2572-2572, 1999
10741999
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
J Fueyo, C Gomez-Manzano, R Alemany, PSY Lee, TJ McDonnell, ...
Oncogene 19 (1), 2-12, 2000
9782000
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse
WKA Yung, MD Prados, R Yaya-Tur, SS Rosenfeld, M Brada, ...
Journal of Clinical Oncology 17 (9), 2762-2771, 1999
9251999
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis
W Yang, Y Xia, D Hawke, X Li, J Liang, D Xing, K Aldape, T Hunter, ...
Cell 150 (4), 685-696, 2012
7982012
MMAC1/PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines
DHF Teng, R Hu, H Lin, T Davis, D Iliev, C Frye, B Swedlund, KL Hansen, ...
Cancer research 57 (23), 5221-5225, 1997
6671997
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
N Zhang, P Wei, A Gong, WT Chiu, HT Lee, H Colman, H Huang, J Xue, ...
Cancer cell 20 (4), 427-442, 2011
6232011
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
HA Fine, WD Figg, K Jaeckle, PY Wen, AP Kyritsis, JS Loeffler, VA Levin, ...
Journal of Clinical Oncology 18 (4), 708-708, 2000
5882000
Phase I study of DNX-2401 (Delta-24-RGD) oncolytic adenovirus: replication and immunotherapeutic effects in recurrent malignant glioma
FF Lang, C Conrad, C Gomez-Manzano, WKA Yung, R Sawaya, ...
Journal of clinical oncology 36 (14), 1419, 2018
5772018
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08
PY Wen, WKA Yung, KR Lamborn, PL Dahia, Y Wang, B Peng, LE Abrey, ...
Clinical Cancer Research 12 (16), 4899-4907, 2006
5022006
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results
FF Lang, JM Bruner, GN Fuller, K Aldape, MD Prados, S Chang, ...
Journal of Clinical Oncology 21 (13), 2508-2518, 2003
4822003
Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas
KR Lamborn, WKA Yung, SM Chang, PY Wen, TF Cloughesy, ...
Neuro-oncology 10 (2), 162-170, 2008
4602008
Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis
T Sano, H Lin, X Chen, LA Langford, D Koul, ML Bondy, KR Hess, ...
Cancer research 59 (8), 1820-1824, 1999
4381999
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
MA Davies, D Koul, H Dhesi, R Berman, TJ McDonnell, D McConkey, ...
Cancer research 59 (11), 2551-2556, 1999
4041999
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway
J Fueyo, R Alemany, C Gomez-Manzano, GN Fuller, A Khan, CA Conrad, ...
Journal of the National Cancer Institute 95 (9), 652-660, 2003
3952003
Longitudinal molecular trajectories of diffuse glioma in adults
FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ...
Nature 576 (7785), 112-120, 2019
3902019
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