Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes GW Thorpe, CS Fong, N Alic, VJ Higgins, IW Dawes Proceedings of the National Academy of Sciences 101 (17), 6564-6569, 2004 | 530 | 2004 |
Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network L Partridge, N Alic, I Bjedov, MDW Piper Experimental gerontology 46 (5), 376-381, 2011 | 338 | 2011 |
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs S Broughton, N Alic, C Slack, T Bass, T Ikeya, G Vinti, AM Tommasi, ... PloS one 3 (11), e3721, 2008 | 226 | 2008 |
The Ras-Erk-ETS-signaling pathway is a drug target for longevity C Slack, N Alic, A Foley, M Cabecinha, MP Hoddinott, L Partridge Cell 162 (1), 72-83, 2015 | 209 | 2015 |
The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila T Ikeya, S Broughton, N Alic, R Grandison, L Partridge Proceedings of the Royal Society B: Biological Sciences 276 (1674), 3799-3807, 2009 | 161 | 2009 |
A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation E Landrieux, N Alic, C Ducrot, J Acker, M Riva, C Carles The EMBO journal 25 (1), 118-128, 2006 | 154 | 2006 |
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ... Molecular systems biology 7 (1), 502, 2011 | 143 | 2011 |
DILP‐producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition SJ Broughton, C Slack, N Alic, A Metaxakis, TM Bass, Y Driege, ... Aging cell 9 (3), 336-346, 2010 | 142 | 2010 |
Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor N Alic, MP Hoddinott, G Vinti, L Partridge Aging cell 10 (1), 137-147, 2011 | 114 | 2011 |
Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk C Slack, C Werz, D Wieser, N Alic, A Foley, H Stocker, DJ Withers, ... PLoS Genetics 6 (3), e1000881, 2010 | 109 | 2010 |
RNA polymerase III limits longevity downstream of TORC1 D Filer, MA Thompson, V Takhaveev, AJ Dobson, I Kotronaki, JWM Green, ... Nature 552 (7684), 263-267, 2017 | 106 | 2017 |
Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress VJ Higgins, N Alic, GW Thorpe, M Breitenbach, V Larsson, IW Dawes Yeast 19 (3), 203-214, 2002 | 89 | 2002 |
Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster N Alic, ME Giannakou, I Papatheodorou, MP Hoddinott, TD Andrews, ... PLoS genetics 10 (9), e1004619, 2014 | 71 | 2014 |
Identification of a Saccharomyces cerevisiae Gene that Is Required for G1 Arrest in Response to the Lipid Oxidation Product Linoleic Acid Hydroperoxide* N Alic, VJ Higgins, IW Dawes Molecular Biology of the Cell 12 (6), 1801-1810, 2001 | 71 | 2001 |
Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription N Alic, N Ayoub, E Landrieux, E Favry, P Baudouin-Cornu, M Riva, ... Proceedings of the National Academy of Sciences 104 (25), 10400-10405, 2007 | 66 | 2007 |
Death and dessert: nutrient signalling pathways and ageing N Alic, L Partridge Current opinion in cell biology 23 (6), 738-743, 2011 | 64 | 2011 |
Cell-nonautonomous effects of dFOXO/DAF-16 in aging N Alic, JM Tullet, T Niccoli, S Broughton, MP Hoddinott, C Slack, D Gems, ... Cell reports 6 (4), 608-616, 2014 | 63 | 2014 |
Nutritional programming of lifespan by FOXO inhibition on sugar-rich diets AJ Dobson, M Ezcurra, CE Flanagan, AC Summerfield, MDW Piper, ... Cell reports 18 (2), 299-306, 2017 | 60 | 2017 |
Lipid hydroperoxides activate the mitogen-activated protein kinase Mpk1p in Saccharomyces cerevisiae N Alic, VJ Higgins, A Pichova, M Breitenbach, IW Dawes Journal of Biological Chemistry 278 (43), 41849-41855, 2003 | 59 | 2003 |
Genome-wide transcriptional responses to a lipid hydroperoxide: adaptation occurs without induction of oxidant defenses N Alic, T Felder, MD Temple, C Gloeckner, VJ Higgins, P Briza, IW Dawes Free Radical Biology and Medicine 37 (1), 23-35, 2004 | 55 | 2004 |