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Tom Mikkelsen
Tom Mikkelsen
Ontario Brain Institute
Verifisert e-postadresse på braininstitute.ca
Tittel
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År
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
cell 155 (2), 462-477, 2013
42892013
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
PY Wen, DR Macdonald, DA Reardon, TF Cloughesy, AG Sorensen, ...
Journal of clinical oncology 28 (11), 1963-1972, 2010
35362010
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
30992018
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
Journal of clinical oncology 27 (28), 4733-4740, 2009
26942009
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
Cancer Genome Atlas Research Network
New England Journal of Medicine 372 (26), 2481-2498, 2015
24832015
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
19162008
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ...
Cell 173 (2), 400-416. e11, 2018
17932018
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
17922018
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
17612012
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
17122018
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ...
Cell 164 (3), 550-563, 2016
16862016
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer
KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ...
Cell 173 (2), 291-304. e6, 2018
15322018
Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment
Q Wang, B Hu, X Hu, H Kim, M Squatrito, L Scarpace, AC DeCarvalho, ...
Cancer cell 32 (1), 42-56. e6, 2017
11322017
Machine learning identifies stemness features associated with oncogenic dedifferentiation
TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ...
Cell 173 (2), 338-354. e15, 2018
10122018
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
L Sun, AM Hui, Q Su, A Vortmeyer, Y Kotliarov, S Pastorino, A Passaniti, ...
Cancer cell 9 (4), 287-300, 2006
8852006
Clonal expansion of p53 mutant cells is associated with brain tumour progression
D Sidransky, T Mikkelsen, K Schwechheimer, ML Rosenblum, ...
Nature 355 (6363), 846-847, 1992
8531992
Transforming fusions of FGFR and TACC genes in human glioblastoma
D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ...
Science 337 (6099), 1231-1235, 2012
7222012
Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas
TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ...
Cell reports 23 (1), 239-254. e6, 2018
6692018
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
6632016
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ...
Cell reports 23 (1), 313-326. e5, 2018
6442018
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Artikler 1–20